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Vol 53(2019) N 2 p. 227-236; DOI 10.1134/S0026893319020134 Full Text

E.S. Pshennikova1*, A.S. Voronina1

Neural Crest-An Unusual Population of Embryonic Cells

1Bach Institute of Biochemistry, Research Center of Biotechnology, Russian Academy of Sciences, Moscow, 119071 Russia

*pshennikova57@mail.ru
Received - 2018-10-11; Revised - 2018-11-20; Accepted - 2018-11-20

The neural crest (NC) in embryos of vertebrates represents a cell population formed at the border of the neural plate. These cells retain pluripotency, express a set of specific markers, and become multipotent upon their migration away from the neural tube to give rise to numerous derivatives. The genes specific for vertebrate NC appeared in evolution long before vertebrates. Abnormal development of NC cells causes numerous pathologies in humans.

neural crest, gene regulatory networks, pluripotency, stem cells



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