JMB-HEADER RAS-JOURNALS EIMB Pleiades Publishing

RUS

             

ENG

YearIMPACT-FACTOR
2021  1,540
2020  1,374
2019  1,023
2018  0,932
2017  0,977
2016  0,799
2015  0,662
2014  0,740
2013  0,739
2012  0,637
2011  0,658
2010  0,654
2009  0,570
2008  0,849
2007  0,805
2006  0,330
2005  0,435
2004  0,623
2003  0,567
2002  0,641
2001  0,490
2000  0,477
1999  0,762
1998  0,785
1997  0,507
1996  0,518
1995  0,502
Vol 48(2014) N 3 p. 319-331; DOI 10.1134/S0026893314030182 Full Text

S.S. Ryazansky*, E.A. Mikhaleva, O.V. Olenkina

Essential Functions of microRNAs in Animal Reproductive Organs

Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182, Russia

*ryazansky@img.ras.ru
Received - 2014-01-20; Accepted - 2014-01-20

The development of the reproductive organs and the gametogenesis in animals are complex and multistage processes that require the precise and efficient regulation. In this review, we summarized the recent findings about the essential functions of microRNAs (miRNAs) in the regulation of gene expression during the differentiation of germ cells in spermatogenesis and oogenesis. Most likely, main and common functions of the conserved and highly expressed miRNAs in the male and female reproductive organs of mammals are the control of differentiation and proliferation of cells. Also we discussed a possible involvement of germline- expressed miRNAs in the formation of reproductive barriers and speciation.

microRNAs, reproductive organs, spermatogenesis, oogenesis, speciation



JMB-FOOTER RAS-JOURNALS