Vol 45(2011) N 2 p. 221-228;
V.V. Zhirkova1*, S.A. Fedorova1, V.L. Akhmetova2, L.A. Zhivotovsky3, E.K. Khusnutdinova2
Allelic polimorphism of six microsatellite DNA loci in population of Sakha (Yakutia)1Yakut Research Center for Complex Medical Problems, Russian Academy of Medical Sciences, Yakutsk, 677010, Russia
2Institute of Biochemistry and Genetics, Ufa Scientific Center, Russian Academy of Sciences, Ufa, 450054, Russia
3Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia
Received - 2010-07-16; Accepted - 2010-08-17
The allele frequency distributions of six STR loci (D3S1358, D16S539, THOI, D8S1179, LPL, and HUMvWFII) used in forensic practice were analyzed in populations of Sakha (Yakutia): three ethnogeographical groups of Sakha (Yakuts), Evenks, Yukagirs, Dolgans, and Russians. There were significant differences between Russians and all other populations by five markers. The total discriminating power (PD) of the locus system studied was assessed for each population. The interpopulation genetic difference (FST) was 0.005. Data on the allelic polymorphism of the above STR loci were used to analyze phylogenetic relationships among the populations of Sakha and those of other regions: East Europe, South Siberia, Chukotka and Kamchatka.
autosomal microsatellite loci, populations of Sakha (Yakutia), genetic diversity