JMB-HEADER RAS-JOURNALS EIMB Pleiades Publishing
RUS

             

 ENG

YearIMPACT-FACTOR
2023  1,500
2022  1,200
2021  1,540
2020  1,374
2019  1,023
2018  0,932
2017  0,977
2016  0,799
2015  0,662
2014  0,740
2013  0,739
2012  0,637
2011  0,658
2010  0,654
2009  0,570
2008  0,849
2007  0,805
2006  0,330
2005  0,435
2004  0,623
2003  0,567
2002  0,641
2001  0,490
2000  0,477
1999  0,762
1998  0,785
1997  0,507
1996  0,518
1995  0,502
Vol 43(2009) N 3 p. 355-359;
S.A. Smirnikhina, A.V. Lavrov

Common methods for cytosine methylation analysis in DNA

Medical Genetic Research Center, Russian Academy of Medical Sciences, Moscow, 115478, Russia
Received - 2008-08-28; Accepted - 2008-09-09

The review considers the methods most commonly used to detect DNA methylation, their advantages, potential limitations, and selection for various purposes. A detailed protocol is described for bisulfite treatment, which is used as a preliminary step in the majority of DNA methylation assays.

DNA methylation, methods of DNA methylation analysis, bisulfite treatment
JMB-FOOTER RAS-JOURNALS