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Vol 45(2011) N 2 p. 343-346; T.N. Bocharova, N.P. Kvitko, E.A. Smirnova, A.A. Volodin* Bimodal Character of the Solubility Isoterm of Histone H1 Complexes with Short Oligonucleotides Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, 123182 Russia*alexvolodin@yahoo.com Received - 2010-07-02; Accepted - 2010-07-15 The complexes of histone H1 with short oligonucleotides are most efficiently precipitated at two histone/DNA weight ratios, approximately equal to 1.3 and 2.5. Such behavior cannot be explained assuming purely electrostatic character of the histone - DNA interaction and suggests the presence of other, probably structural factors. DNA condensation, linker histone, oligonucleotides |
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