Journal of Molecular Biology

Year	IMPACT-FACTOR
2023	1,500
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1995	0,502

Vol 49(2015) N 6 p. 928-932; DOI 10.1134/S0026893315060175

O.E. Melkina¹, V.Yu. Kotova¹, M.N. Konopleva², I.V. Manukhov^1,2, K.S. Pustovoit¹, G.B. Zavilgelsky¹*

Photoreactivation of UV-exposed Escherichia coli K12 AB1886 uvrA6 via luminescence of Photobacterium leiognathi luciferase
¹GosNIIgenetika State Research Center, Moscow, 117545 Russia;
²Moscow Institute of Physics and Technology (State University), Dolgoprudnyi, Moscow Region, 141700 Russia

^*zavilgel@genetika.ru
Received - 2015-05-14; Accepted - 2015-05-25

Bioluminescence induced by luciferases of marine bacteria promotes repair of UV-damaged DNA in Escherichia coli AB1886 uvrA6. Bacterial photolyase, which implements photoreactivation activity, was identified as a major contributor to DNA repair. However, a UV-induced increase in bioluminescence (SOS induction) of bacterial cells was insufficient for efficient photoreactivation.

bioluminescence, photolyase, photoreactivation, SOS induction