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Vol 47(2013) N 1 p. 120-122; I.G. Nikitina1*, Yu.A. Bukurova1, S.L. Hankin2, V.L. Karpov1, N.A. Lisitsyn1, S.F. Beresten1 Secretion of Enteric α-Defensin 5 into Bloodstream by Colon Tumors 1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 119991 Russia2Medical Center of the Bank of Russia, Moscow, 117593 Russia *nikitinainna87@yandex.ru Received - 2012-02-20; Accepted - 2012-04-19 The screening for enteric α-defensin was performed in the blood serum of oncology patients and healthy donors. Enteric α-defensin was not detected in all serum samples from five healthy donors, while serum samples from two of the five oncology patients had the processed form of this protein. The acquired results allow us to suggest the possibility of the serological diagnostics of large intestinal tumors in high-risk groups. α-defensin 5, tumor markers, Paneth cells, high affinity antibodies, serological diagnostics, colon tumors |
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