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Vol 37(2003) N 6 p. 888-896; S.L. Grokhovsky, S.A. Strel'tsov, A.L. Zhuze Interaction of Topotecan, DNA Topoisomerase I Inhibitor, with Double-Stranded Polydeoxyribonucleotides. 5. Topotecan is Capable of Producing Single- and Double-Strand Breaks in Circular Supercoiled DNA in the Absence of the Enzyme Received - 2002-12-25; in final form - 2003-04-11 |