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Vol 46(2012) N 4 p. 548-556; E.S. Gerasimov*, N.S. Efimova, A.A. Kolesnikov** Three Patterns of Trypanosomatid Cryptogene Structural Organization Biological Faculty, Moscow State University, Moscow, 119992 Russia*jalgard@yandex.ru **sasha@protein.bio.msu.su Received - 2011-12-05; Accepted - 2012-01-13 The structures of some cryptogenes of previously unstudied species of homoxenous trypanosomatids that belong to different phylogenetic groups has been analyzed. New examples of the editing domain length reduction for A6 and COIII were found. A comparative analysis of the sequences allowed us to divide the cryptogenes into three groups (patterns) according to not only the evolutionary variations in the length of the edited domain, but also the degree of conservation of the nucleotide sequence. The potential factors that determine variants of the cryptogene structure are discussed. In addition, the alternative editing of the rps12 transcript of Wallaceina sp. Wsd has been demonstrated. editing domain, cryptogene, trypanosomatids, retroposition model, alternative editing |
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