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Vol 48(2014) N 4 p. 520-545; DOI 10.1134/S0026893314040128  M.G. Sharapov*, V.K. Ravin, V.I. Novoselov Peroxiredoxins as Multifunctional Enzymes Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, 142290 Russia*sharapov.mg@yandex.ru Received - 2014-02-20 Peroxiredoxins are an evolutionary ancient widespread group of selenium-independent peroxidases. Peroxiredoxins protect cells from various peroxides, play an important role in maintaining redox homeostasis, and are additionally involved in transmitting extracellular and intracellular signals. The review considers peroxiredoxins from different kingdoms of living organisms and discusses the recent data on their structure, function, and the expression regulation of their genes. peroxiredoxins, structure, function, gene expression regulation, regulation of enzymatic activity, oxidative stress |
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